MD Codes Filler: What Do the Codes Mean?

MD Codes Filler: What Do the Codes Mean?

Jangju Kim22 min readEditorial policy

Key takeaways

  • What a code is: letters for a facial area (Ck is the cheek), a number for a smaller part of it (Ck1 is the zygomatic arch), plus depth, tool, technique and a minimum amount.
  • Red codes: alert areas near sensitive structures, where the paper reminds injectors to be cautious with needles and to consider cannulas.
  • What it isn't: a filler brand or a fixed recipe; the numbers are a checklist, not an injection order.
  • Evidence: a methods paper with three case studies and a 12-patient retrospective study, written by consultants to one filler maker.

An MD Code is a short label, such as Ck1, for one injection point on the face: in the 2021 paper that first described the system in a peer-reviewed journal, each code carries the target depth, the tool (needle or cannula), the injection technique and a minimum product amount. MD Codes is a planning and teaching method for hyaluronic acid (HA) filler, not a filler product, and which points apply to your face is decided at the exam.

There are other ways to look at MD Codes, such as how long filler lasts or what it costs, but this article explains one thing: what a single code marks and what it leaves out. Every number below comes from published papers, not from STON Clinic patients.

What Does an MD Code Stand For?

What Does an MD Code Stand For?What Does an MD Code Stand For?

Each code names one injection site. The 2021 paper explains that the MD Codes are letters, numbers, shapes, and colors, and that the letters signify anatomical units (e.g., the cheek, temple, or chin) and the numbers signify subunits. Its own example: the cheek is represented by the letters Ck, and subunits of the cheek are numbered, so Ck1 = zygomatic arch and Ck2 = zygomatic eminence. The paper also marks the side of the face, so the same point on the right and left can be told apart.

Behind each label sits a set of instructions. According to the paper's summary, each MD Code includes information regarding the target depth of injection, the proper delivery tool (needle or cannula) and delivery technique (e.g., aliquot, bolus, fanning), and the minimum product volume recommended to achieve visible, reproducible results, which the author calls the active number. In short, a code is shorthand that lets two injectors mean the same spot, layer and method.

What Do the Layer and Tool in a Code Tell You?

What Do the Layer and Tool in a Code Tell You?What Do the Layer and Tool in a Code Tell You?

They tell you where the product is meant to sit and how it gets there. Some codes aim at the bone surface (supraperiosteal, meaning just on top of the bone), others at the layer under the skin. The FDA notes that approved dermal fillers are supplied for injection using a syringe with a needle or cannula, and the code says which of the two the method suggests for that point.

The table lists a few codes from the 2021 paper's own table, with the caution note the paper attaches. It describes the author's method, not a plan for any one person.

CodeAreaTarget layerToolCaution note in the paper
Ck1Zygomatic arch (cheekbone)On the boneNeedle—
Ck3Front inner cheekOn the boneNeedleInfraorbital artery
T1Front templeOn the boneNeedleSuperficial frontal artery, deep temporal arteries
Tt1Center of the under-eye hollowOn the boneCannulaBranches of the infraorbital artery
M1Upper marionette lineJust under the skinNeedle—
Lp7Philtrum column (ridge above the lip)Just under the skinNeedle—

The paper lists other options for some of these sites, and other units (chin, jawline, forehead, nose) have their own codes. The point of the table is the pattern: one code ties one spot to one layer and one tool.

What Do the Layer and Tool in a Code Tell You?What Do the Layer and Tool in a Code Tell You?

Why Are Some Codes Red?

Why Are Some Codes Red?Why Are Some Codes Red?

Red marks an alert area. The paper says that MD Codes in red denote alert areas, where there are sensitive structures, such as neurovascular bundles in facial danger zones. These red codes remind the clinician to be cautious in these areas when using needles and to consider the use of cannulas instead, and the paper adds that the alert codes should never be used to guide injection by novice clinicians.

That caution lines up with what the FDA calls the most concerning risk of dermal fillers: unintentional injection into a blood vessel, leading to blocked blood vessels and poor blood supply to tissues. A red code is a reminder for the injector. It does not mean the area is off limits, and a code without red does not mean a point carries no risk.

Is MD Codes a Filler Product?

Is MD Codes a Filler Product?Is MD Codes a Filler Product?

No. It is a method for describing and planning HA filler injections. The 2021 paper describes itself as the first peer-reviewed description of the MD Codes system and its algorithms, and its author, Maurício de Maio, has served as a consultant for Allergan plc, a filler maker.

So "MD Codes filler" does not name a syringe or a brand. The product, the amount and the depth are separate choices. The FDA notes that the time that the effect lasts depends on the filler material and the area where it is injected, and the code itself does not change that.

How Strong Is the Evidence Behind MD Codes?

How Strong Is the Evidence Behind MD Codes?How Strong Is the Evidence Behind MD Codes?

It is early and comes mostly from the people who built the method. The 2021 paper rated its own level of evidence as IV and illustrated the system with three case studies. A later retrospective analysis looked back at 12 adult women from the Netherlands who were treated with about 12 mL of HA fillers each at an MD Codes training event, with patients selected based on their appropriateness for the training. All authors were consultants for the filler maker whose products were used.

SourceDesignWhoWhat was reported
2021 methods paperDescription with three case studies; level of evidence IV2 women, 1 manHow codes and algorithms were applied
2023 retrospective studyRetrospective, photos rated by patients and 49 observers from 12 countries; patient questionnaires at 6 and 9 months12 women, one training sessionAt 9 months, 11 of 12 said they looked "less tired", 8 of 12 "less saggy", 6 of 12 "less sad"; no serious side effects reported
2025 commentaryOpinion paper by other authors—Feature-based methods such as MD Codes may not address overall facial balance or skeletal asymmetry

These are small groups under their own conditions, and the 9-month answers are the patients' own questionnaire replies. They describe those participants, not what one person will see. The 2025 commentary argues that such methods may neglect the underlying skeletal asymmetries, and that a comprehensive approach that includes a detailed assessment by skilled practitioners is essential.

Does the Code Number Set the Order or the Amount?

Neither, on its own. The 2021 paper states that the MD Codes numbers do not reflect the sequence in which the injections should be administered, but instead provide a checklist of items that the clinician can mark when assessing each facial unit. Ck3 is not the third injection; it is the third box on the cheek checklist.

Order comes from the algorithms layered on top. The paper says codes are selected using algorithms focused on lessening a saggy, tired, sad, or angry look, and a narrative review of the eye area describes how the method identified which points should be prioritized to cause greater aesthetic impact. The "active number" in each code is the author's suggested minimum, not a dose set for your face.

Does the Code Number Set the Order or the Amount?Does the Code Number Set the Order or the Amount?

Questions Worth Asking About a Code-Based Plan

If a clinic mentions codes or points, the useful questions are about your face, not the label. Ask which areas the plan covers and why, which layer each point targets, whether a needle or a cannula is planned near alert areas, and how swelling or a blocked vessel would be checked and handled. The FDA also suggests you ask your health care provider about their training and experience injecting dermal fillers.

STON Clinic's Hyaluronic Acid Filler Page

STON Clinic's page on hyaluronic acid filler says that how long it holds depends on the product, the area and your own condition, and that whether a treatment suits you is decided by the physicians after an examination, with results and side effects varying from person to person.

Filler consultations are available at Lotte Hotel Seoul Main Tower 9F, 30 Eulji-ro, Jung-gu, Seoul, in Myeongdong near Euljiro 1(il)-ga Station on Line 2.

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References

  1. MD Codes methodological approach, full text with code table (de Maio, 2021) — PubMed Central
  2. MD Codes: A Methodological Approach to Facial Aesthetic Treatment with Injectable Hyaluronic Acid Fillers (de Maio, 2021) — PubMed
  3. Dermal Fillers (Soft Tissue Fillers) — U.S. Food and Drug Administration
  4. Applying the MD Codes to Treat Emotional and Social Attributes with HA Fillers: A Retrospective Serial Case Study (2023) — PubMed Central
  5. Challenges with Conventional Dermal Filler Guidelines: Considering Multi-Axes Facial Rotation Asymmetry Patterns (2025) — PubMed
  6. Periorbital Filling With The MD Codes Algorithm: A Narrative Review and a Practical Guide (2021) — PubMed

Frequently asked questions

Q. What do MD Codes mean in filler?

A. Each MD Code is a label for one injection point on the face, such as Ck1 for the zygomatic arch. In the 2021 paper, each code carries the target depth, needle or cannula, technique and a minimum product amount. Which points apply to you is decided at the exam.

Q. Is MD Codes a type of filler?

A. No. It is a method for planning and teaching HA filler injection. The product, amount and depth are separate choices, and the author has served as a consultant for a filler maker.

Q. What does a red MD Code mean?

A. Red marks an alert area near sensitive structures such as nerves and vessels. The paper reminds injectors to be cautious with needles there, to consider cannulas, and says novice clinicians should not use those codes to guide injection.

Q. Does the number in a code mean the order of injection?

A. No. The paper says the numbers are a checklist for each facial area, not a sequence. Priority comes from separate algorithms aimed at looks such as tired or saggy.

Q. How strong is the evidence for MD Codes?

A. Early. The main papers are a methods paper rated level of evidence IV with three case studies and a 12-patient retrospective analysis, both by consultants to one filler maker. A 2025 commentary argues such methods may miss overall facial balance and skeletal asymmetry.

Q. Can I ask for specific MD Codes at my consultation?

A. You can describe the area that bothers you and ask which points, layers and tools are planned, and how complications would be handled. Whether a treatment suits you is decided after an examination.

Jangju Kim

Jangju Kim Senior Director

JANGJU KIM

Dr. Jangju Kim is a clinic director at STON Clinic, LOTTE HOTEL in Myeongdong.

Career / Education

  • Current) Director of STON Clinic, LOTTE HOTEL Myeongdong
  • Graduated from Kyung Hee University College of Medicine
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